Luteolin affects keloid fibroblast proliferation and apoptosis by regulating FRAT1 gene expression
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/32538769
其他信息:
PMID: 32538769
作者: Xueyan Zhang; Wen Liu; Shuxiang Wei; Xueyan Zhang; Xueyan Zhang; ...
摘要: The current experiment was performed to investigate whether luteolin affects the proliferation and apoptosis of keloid fibroblasts by regulating the expression of FRAT1 gene. Keloid fibroblasts were treated with luteolin at different concentrations. MTT method, western blot, flow cytometry, and real-time quantitative PCR (qPCR) were used to detect cell proliferation, cyclin D1 (CyclinD1), p21, B-cell lymphoma / leukemia-2 (Bcl-2), Bcl-2 related X protein (Bax), FRAT1 protein expression, apoptosi...
