From Flat to 3D: Replacing Phenyl Rings with Saturated Bridged Bicyclic Mimetics to Mitigate Bioactivation and Optimize ADME Properties and Oral Bioavailability in Reverse Amide Orientation
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DOI: https://doi.org/10.1021/acs.jmedchem.5c03656
文献链接: https://pubs.acs.org/doi/10.1021/acs.jmedchem.5c03656
其他信息:
出版社: American Chemical Society (ACS)
作者: Murugaiah A. M. Subbaiah; Shruti Surendran; Gaurav Saini; Lavanya Billava Ramappa; Sivashankaran Raju; Joyson Nandha; Himangshu Bhowmik; Enugurthi Krishna; Sushmita Janrao; Vijay Kumar; Shruti Shikha Choubey; Joothipriya Subramanian; Bhuvaneshwaran Anandamoorthy; Sukanta Kumar Sahoo; Raghavendra Veerapuram; Korlepara Vamsi Krishna; Manohar Yelleswarapu; Yogesh Kumar Gupta; Muthalagu Vetrichelvan; Anuradha Gupta; Salil Desai; Thanga Mariappan; Arvind Mathur; Prakash Ramaseshan Vachaspati
全文下载地址: https://pubs.acs.org/doi/pdf/10.1021/acs.jmedchem.5c03656
