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Glypican-3——靶向PET成像用于肝细胞癌精准诊断：从实验台到床边复制

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林志、李姆、潘志、胡、冯、张......——临床癌症......，2025年 aacrjournals.org
目的：本研究旨在开发和评估一种新型基于草甘-3（GPC3）的靶向单链变片段PET放射示踪剂，用于在临床前模型及首例人体临床研究中，非侵入性评估GPC3表达并精确诊断肝细胞癌（HCC）。实验设计：新型抗GPC3单链变异片段XH-06，用镓-68标记得到[68Ga] Ga-XH-06。细胞摄取检测、小动物PET成像和生物分布研究......

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