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Preclinical development of MHB042C: A next-generation anti-c-Met ADC conjugating VHH-Fc fusion protein with a novel topoisomerase I inhibitor复制

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B Liu, L Zhu, Y Chen, X Meng, A Li, L Liu, Z Yao…
Cancer …, 2025
aacrjournals.org
… The smaller VHH-Fc fusion protein offers higher potential for tumor tissue penetration …
Additionally, Fc function was silenced to minimize nonspecific ADC uptake. The payload, …

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