Responders to biologics in severe uncontrolled chronic rhinosinusitis with nasal polyps: a multicentric observational real-life study
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/39660730/
其他信息:
G Mortuaire, E Béquignon, C Daveau…
…, 2025
pubmed.ncbi.nlm.nih.gov
Background Clinical trials have demonstrated the effectiveness of biologics in treating chronic rhinosinusitis with nasal polyps (CRSwNP). However, real-world evidence regarding patient outcomes and predictors of clinical response remains limited. Methodology In this multicentric 18-month follow-up study, 326 adult patients who initiated biologic therapy for severe uncontrolled CRSwNP were included. Patient characteristics, including clinical and inflammatory markers, and comorbidities were collected at baseline and at 3, 6, 12, and 18 …
