期刊论文[Calcipotriol]复制

DOI:复制

文献链接: https://pubmed.ncbi.nlm.nih.gov/11319386复制

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PMID: 11319386
作者: J J Guilhou; J J Guilhou; J J Guilhou
摘要: Calcipotriol is a vitamin D derivative synthesized in 1985 by the Léo Laboratories. Its mode of action is identical to that of 1-25 vitamin D3 (calcitriol), essentially by regulating the activity of genes capable of responding to vitamin D. Calcipotriol leads to reduction in keratinocyte proliferation and induces their differentiation as well as having important immunomodulator functions. Toxicology studies have demonstrated that phosphorus calcium metabolism anomalies are only observed for dose...