期刊论文Construction of axial chirality via palladium/chiral norbornene cooperative catalysis复制

DOI:复制

文献链接: 10.1038/s41929-020-0494-1复制

其他信息:

ZS Liu, Y Hua, Q Gao, Y Ma, H Tang, Y Shang…
Nature Catalysis, 2020
nature.com
Axially chiral biaryls are common structural motifs in functional materials, bioactive natural products, pharmaceuticals and chiral catalysts/ligands. As such, efficient preparation of these privileged scaffolds is an important endeavour in organic chemistry. Herein we report a general and modular platform technology for the construction of axial chirality via palladium/chiral norbornene cooperative catalysis. It is a three-component cascade process that involves widely available aryl iodides, 2, 6-substituted aryl bromides and olefins (or …