1366-P: Examining Central Carbon Metabolic Flux in the Perfused Exocrine Pancreas Using Dissolution Dynamic Nuclear Polarization
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A Rushin, M Mcleod, M Ragavan, M Merritt
Diabetes, 2022
diabetesjournals.org
The pancreas functions as both an endocrine and exocrine gland. The endocrine component consists of the islets of Langerhans, whereas the exocrine tissue produces digestive enzymes through the ductal system. Although the majority of Type I Diabetes research has focused on the islets, the exocrine tissue is likely implicated in T1D as well. This research utilizes a novel method to investigate exocrine pancreas metabolism with a pancreas perfusion system. I hypothesized that dissolution dynamic nuclear polarization …
