Safety and efficacy of desonide hydrogel 0.05% in pediatric subjects with atopic dermatitis.
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AA Hebert, FE Cook-Bolden, S Basu…
Journal of drugs in …, 2007
europepmc.org
Low to mid potency corticosteroids remain a cornerstone of therapy for atopic dermatitis (AD). Since AD is most prevalent in the younger pediatric population and is chronic in nature, safety is of particular concern especially for children under 2 years of age. A novel desonide (0.05%) formulation was developed in a nonirritating and moisturizing aqueous gel (hydrogel) that is free of alcohol and surfactants. The safety and efficacy of this new class VI low potency topical steroid was substantiated in 2 phase III clinical trials in mild to …

