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APOE loss-of-function variants: Compatible with longevity and associated with resistance to Alzheimer's disease pathology复制

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A Chemparathy, Y Le Guen, S Chen, EG Lee, L Leong…
Neuron, 2024
cell.com
… of APOE loss of function (LoF) on AD pathogenesis is unknown. We searched for APOE LoF variants … and identified seven heterozygote carriers of APOE LoF variants. Five carriers were …

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