Progress of neuroimmunotherapies: Witnessing an impressive success in the treatment of neurologic autoimmunities
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MC Dalakas
Handbook of Clinical Neurology, 2026
Elsevier
This introductory chapter describes the evolution of immunotherapies in neurology as witnessed from the late 1970s to early 1980s, when the main therapy for all autoimmune neurologic diseases was only oral and IV steroids, to the present. The growing pains, complexities, challenges, and the very slow pace by which newer immunotherapeutic options were evolving are discussed pointing out that effective new therapies started to evolve many years later in the late 1990s to 2000 with plasmapheresis, IVIg, and β …
