Human pain neuroscience and the next generation of pain therapeutics
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BA Copits, M Curatolo, PM Dougherty, RW Gereau…
Neuron, 2025
cell.com
The recent approval of suzetrigine for acute pain treatment highlights both the success of targeting peripheral sensory neurons for pain management and the potential of developing new pain therapies primarily in human-based systems. To realize this transformative potential, further research into somatosensation and pain neuroimmunology in human systems is essential.