Pembrolizumab plus weekly paclitaxel in platinum-resistant recurrent ovarian cancer (ENGOT-ov65/KEYNOTE-B96): a multicentre, randomised, double-blind, phase 3 …
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N Colombo, E Zsiros, G Parma, E Rulli, A Sebastianelli…
The Lancet, 2026
thelancet.com
Background Epithelial ovarian cancer frequently recurs and becomes resistant to platinum chemotherapy. We investigated whether adding pembrolizumab to weekly paclitaxel, with or without bevacizumab, improves progression-free survival and overall survival compared with weekly paclitaxel, with or without bevacizumab, in participants with platinum-resistant recurrent ovarian cancer who had received one to two 2 previous systemic regimens. Methods ENGOT-ov65/KEYNOTE-B96 is a randomised, double-blind, phase 3 study …
