Inorganic fluoride nephrotoxicity: prolonged enflurane and halothane anesthesia in volunteers.
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RI Mazze, RK Calverley, NT Smith
Anesthesiology, 1977
europepmc.org
The effects of prolonged enflurane and halothane administration on urine-concentrating ability were determined in volunteers by examining their responses to vasopressin before anesthesia and on days 1 and 5 after anesthesia. A significant decrease in maximum urinary osmolality of 264 /-34 mOsm/kg (26 per cent of the preanesthetic value) was present on day 1 after enflurane anesthesia, whereas subjects anesthetized with halothane had a significant increase in maximum urinary osmolality of 120 /-44 mOsm/kg. Serum inorganic …
