Disposition and tissue distribution of angiopeptin in the rat
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/1680648
其他信息:
PMID: 1680648
作者: S S Cathapermal; M L Foegh; C S Rau; P W Ramwell; S S Cathapermal; ...
摘要: The disposition and tissue distribution of angiopeptin, a long-acting octapeptide analogue of somatostatin, were studied in rats following single iv and sc administration of the drug. Similar plasma levels and excretion values of angiopeptin were observed by using radioimmunoassay and radiolabeling techniques. Angiopeptin was absorbed fairly rapidly, with a mean peak plasma level of 25 +/- 4.1 ng/ml at 10-15 min after administration. The kinetics of angiopeptin following sc administration closel...
