Behavioural alterations in rats induced by single prenatal exposure of haloperidol
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/10085779
其他信息:
PMID: 10085779
作者: K P Singh; A K Jaiswal; M Singh; S K Bhattacharya; K P Singh; ...
摘要: Haloperidol (50 mg/kg, i.p.) treatment was given once to two different groups of pregnant Charles Foster rats on gestational day 9 and 14, these being respectively the critical periods of neural morphogenesis and rapid neural cell proliferation in this species. Pregnant control rats were similarly treated with equal volume of vehicle. The pups born were subjected to open-field exploratory behaviour and elevated plus-maze behaviour tests of anxiety and learned helplessness test of depression at 9...
