The sequence of inflammation, relevant biomarkers, and the pathogenesis of acne vulgaris: what does recent research show and what does it mean to the clinician?
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DOI:
文献链接: https://pubmed.ncbi.nlm.nih.gov/23986176
其他信息:
PMID: 23986176
作者: James Q Del Rosso; Leon H Kircik; James Q Del Rosso; James Q Del Rosso; Leon H Kircik
摘要: Acne vulgaris (AV) remains one of the most common skin disorders seen in dermatology practices worldwide. Despite an abundance of publications, AV continues to be a formidable therapeutic challenge due to its complex pathogenesis and chronicity. Regarding the sequence of AV lesion formation, the traditional model teaches that the primary lesion is the microcomedone, a subclinical lesion caused by follicular hyperkeratinization. From the microcomedone, visible AV emerges with development of comed...

