Mutant Forms of Nucleoside Phosphorylases and Other Nucleic Acid Metabolism Enzymes for the Optimization of Cascade Synthesis of Modified Nucleosides
1. 请及时下载文件确认是否正确, 系统将在 2026-09-29 14:41:35 删除文件
2. 如若文件有误请驳回应助文件, 求助状态即回到求助中
3. 如若文件正确请及时点击确认, 若超过时后系统自动默认为已完结
注: 所有应助的资源仅供学习交流使用, 不得违反相关法律法规
DOI:
文献链接:
其他信息:
EA Zayats, YA Abramchik, MA Kostromina…
Russian Journal of …, 2026
Springer
Modified nucleoside drugs are used in clinical practice to treat oncohematological diseases (nelarabine, fludarabine, cladribine, clofarabine) and viral infections (vidarabine, ribavirin, etc.) in the human body. The development of efficient technologies for the production of pharmaceutical substances is an important task for medical biotechnology. There are two main approaches to the synthesis of modified nucleosides: chemical and enzymatic. Traditional chemical synthesis technologies are often complex, labor-intensive, and …
